{"id":11928,"date":"2023-07-17T16:35:17","date_gmt":"2023-07-17T20:35:17","guid":{"rendered":"https:\/\/research.ncsu.edu\/administration\/?page_id=11928"},"modified":"2025-06-03T14:20:56","modified_gmt":"2025-06-03T18:20:56","slug":"iacuc-application-review-process","status":"publish","type":"page","link":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-application-review-process\/","title":{"rendered":"Step 3: Application Review Process"},"content":{"rendered":"\n\n\n\n\n<p class=\"is-style-intro-copy\">New protocol submissions and amendment requests for approved protocols are submitted to the IACUC office by the Principal Investigator.&nbsp; Significant Protocol amendment requests are processed and reviewed the same as new protocols. <\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Types of Review<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/protocol-and-amendment-review\/\">Pre-review, Designated Member review and full committee reviews<\/a> for new protocols submissions, 3-year rewrites and amendments<\/li>\n\n\n\n<li><a rel=\"noreferrer noopener\" href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/\" target=\"_blank\">Administrative Review Procedures<\/a><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">How to Address Comments on Your Protocol<\/h3>\n\n\n\n<p>These resources cover how to address comments made by IACUC reviewers on a protocol that has already been approved<\/p>\n\n\n<div class=\"is-text wp-block-ncst-buttons\">\n    \n<div class=\"is-style-secondary wp-block-ncst-button\">\n      <a\n        class=\"ncst-block__button-link btn\"\n        href=\"https:\/\/go.ncsu.edu\/red-iacuc-comments-qref:website\"\n        data-ncst-lightbox=\"false\"\n         target=\"_blank\"          rel=\"noreferrer noopener\"       >\n                  <span class=\"text\">Guide<\/span><span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n\t\t\t\n\t\t\t<use xlink:href=\"#wolficon-arrow-right-bold\">\n\t\t<\/svg><\/span>\n              <\/a>\n    <\/div>\n  \n\n<div class=\"is-style-secondary wp-block-ncst-button\">\n      <a\n        class=\"ncst-block__button-link btn\"\n        href=\"https:\/\/go.ncsu.edu\/red-iacuc-comments-vid:website\"\n        data-ncst-lightbox=\"false\"\n                      >\n                  <span class=\"text\">Video<\/span><span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n\t\t\t\n\t\t\t<use xlink:href=\"#wolficon-arrow-right-bold\">\n\t\t<\/svg><\/span>\n              <\/a>\n    <\/div>\n  \n\n  <\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"reviewtimeframe\">Estimated Review Timeframe for Protocols and Amendments<\/h3>\n\n\n\n<p>Full committee meetings are held on the third Thursday of each month.&nbsp; New protocols should be submitted at least 2 weeks in advance to allow pre-review of the submission.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Full Committee Review Approval (New Category E protocols or amendments): 6-7 weeks<\/li>\n\n\n\n<li>Designate Member Review Approval (Amendments with significant changes or Category C\/D protocols): 3-5 weeks<\/li>\n\n\n\n<li>Administrative Review (Amendments with minor changes): same day to 1 week<\/li>\n<\/ul>\n\n\n<blockquote class=\"wp-block-ncst-blockquote\">\n    <p>These timeframes are for planning purposes only. Some protocols may be completed sooner or take longer, depending on the details.<\/p>\n  <\/blockquote>\n\n\n<div class=\"ncst-content-card migrated-html-box wp-block-ncst-html-box has-gray-600-background-color with-cta\">\n    \n    <div class=\"content-card__text-container\">\n        \n                    <h3 class=\"content-card__headline\">IACUC Lifecycle<\/h3>\n        \n                    <div class=\"content-card__teaser\">\n                <ol class=\"wp-block-list\"><!-- wp:list-item -->\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-determining-if-approval-is-required\/\">Determining if Approval is Required<\/a><\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-preparing-and-submitting-an-application-for-vertebrate-animal-use-avau\/\">Preparing and Submitting an Application for Vertebrate Animal use (AVAU)<\/a><\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-application-review-process\/\">Application Review Process<\/a><\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-responsibilities-after-initial-approval\/\">Responsibilities after Initial Approval<\/a><\/li>\n<!-- \/wp:list-item -->\n\n<!-- wp:list-item -->\n<li><a href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-closing-a-study-iacuc-protocol\/\/\">Closing a Study\/ IACUC Protocol<\/a><\/li>\n<!-- \/wp:list-item --><\/ol>\n            <\/div>\n        \n            <a\n            class=\"ncst-content-card migrated-html-box wp-block-ncst-html-box has-gray-600-background-color with-cta\"\n            href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/\"\n            data-ua-cat=\"Content Card\"\n            data-ua-action=\"Content Card Click\"\n            data-ua-label=https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/\n        >\n            <p class=\"content-card__cta\"><span class=\"text\">View full lifecycle<\/span><span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n\t\t\t\n\t\t\t<use xlink:href=\"#wolficon-arrow-right-bold\">\n\t\t<\/svg><\/span><\/p>\n        <\/a>\n        <\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>New protocol submissions and amendment requests for approved protocols are submitted to the IACUC office by the Principal Investigator.&nbsp; Significant Protocol amendment requests are processed and reviewed the same as&hellip;<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":249,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"views\/homepage.blade.php","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/floating-box-header","ncst_dynamicHeaderData":"{\"backgroundColor\":\"red-400\",\"boxPosition\":\"left\",\"ctaNum\":\"one\",\"useCTA\":false,\"imageURL\":\"https:\/\/research.ncsu.edu\/administration\/files\/2023\/07\/20230712_IACUC-LifeCycle_Step3.png\",\"imageID\":11907}","ncst_content_audit_freq":"","ncst_content_audit_date":"","ncst_content_audit_display":false,"ncst_backToTopFlag":"","footnotes":""},"tags":[],"class_list":["post-11928","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Step 3: Application Review Process - Research Administration and Compliance<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-application-review-process\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Step 3: Application Review Process - Research Administration and Compliance\" \/>\n<meta property=\"og:description\" content=\"New protocol submissions and amendment requests for approved protocols are submitted to the IACUC office by the Principal Investigator.&nbsp; 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