{"id":1241,"date":"2022-05-25T12:53:42","date_gmt":"2022-05-25T16:53:42","guid":{"rendered":"https:\/\/research.ncsu.edu\/administration\/?page_id=1241"},"modified":"2026-02-16T10:37:06","modified_gmt":"2026-02-16T15:37:06","slug":"iacuc-administrative-review-procedures","status":"publish","type":"page","link":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/","title":{"rendered":"Administrative Review Procedures"},"content":{"rendered":"\n\n\n\n\n

Overview<\/h2>\n\n\n\n

Clarification or minor modifications of proposed changes may be addressed through the administrative review process at the discretion of the veterinarian, IACUC chair and\/or IACUC staff. Any significant concerns or questions raised through the administrative review process will result in referral of the renewal or modification request to Designated Member Review (DMR) or Full Committee Review (FCR). Modifications that result in different or additional hazards to personnel do not qualify for administrative review.<\/p>\n\n\n\n

Standard<\/h2>\n\n\n
\n
\n \n
\n \n \n <\/span>\n <\/span>\n

Change in Personnel<\/h2>\n <\/summary>\n

\n \n\n

The IACUC staff may approve deletion, addition or modification of duties for personnel other than the principal investigator (PI). All qualifications as previously set forth by the IACUC must be met prior to such approval. <\/strong><\/p>\n\n\n <\/p>\n <\/details>\n\n\n

\n \n \n <\/span>\n <\/span>\n

Change in Funding Source<\/h2>\n <\/summary>\n

\n \n\n

The IACUC staff may approve deletion or addition of funding sources.<\/p>\n\n\n <\/p>\n <\/details>\n\n\n

\n \n \n <\/span>\n <\/span>\n

Changes in Title or Other Minor Wording Changes in the Protocol<\/strong><\/h2>\n <\/summary>\n

\n \n\n

Title changes, provided that there is no change in objectives or modification of methods or procedures. Changes to fix typos or to adjust study timelines that do not impact animal wellbeing.<\/p>\n\n\n <\/p>\n <\/details>\n\n\n

\n \n \n <\/span>\n <\/span>\n

Changes in Animals to be Used<\/h2>\n <\/summary>\n

\n \n\n

The Addition or change in the age, source or strain that does not increase potential pain or distress or require veterinary review for special husbandry or clinical care of the animals or new strains. (ie-no adverse or lethal phenotypes, or decreased immunocompetency)<\/p>\n\n\n\n

Less than 10% increase in the number of non USDA regulated animals used is considered a significant change that the IACUC has approved for administrative approval; for a USDA-regulated species, any increase is considered a significant change which must go through DMR or FCR review. <\/p>\n\n\n <\/p>\n <\/details>\n\n\n

\n \n \n <\/span>\n <\/span>\n

Changes in Housing Location<\/h2>\n <\/summary>\n

\n \n\n

The addition or change of a location or PI lab or the addition of a transportation change such as a personal vehicle. Both types of change must have assurance of being previously inspected by the IACUC within the last six months.<\/p>\n\n\n <\/p>\n <\/details>\n\n\n <\/div>\n <\/div>\n\n\n

\n \n
\n \n Return to IACUC Homepage<\/span>\n\t\t\t\n\t\t\t\n\t\t<\/svg><\/span>\n <\/a>\n <\/div>\n \n\n <\/div>\n","protected":false},"excerpt":{"rendered":"

Overview Clarification or minor modifications of proposed changes may be addressed through the administrative review process at the discretion of the veterinarian, IACUC chair and\/or IACUC staff. Any significant concerns…<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":1180,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/default-header","ncst_dynamicHeaderData":"{\"pageIntro\":\"Minor modifications to previously approved animal activities may qualify for administrative review by IACUC staff or LAR veterinarians serving as members of the IACUC.
\"}","ncst_content_audit_freq":"","ncst_content_audit_date":"","ncst_content_audit_display":false,"ncst_backToTopFlag":"","footnotes":""},"tags":[],"class_list":["post-1241","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nAdministrative Review Procedures - Research Administration and Compliance<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Administrative Review Procedures - Research Administration and Compliance\" \/>\n<meta property=\"og:description\" content=\"Overview Clarification or minor modifications of proposed changes may be addressed through the administrative review process at the discretion of the veterinarian, IACUC chair and\/or IACUC staff. Any significant concerns…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/\" \/>\n<meta property=\"og:site_name\" content=\"Research Administration and Compliance\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-16T15:37:06+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/iacuc-administrative-review-procedures\\\/\",\"url\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/iacuc-administrative-review-procedures\\\/\",\"name\":\"Administrative Review Procedures - Research Administration and Compliance\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/#website\"},\"datePublished\":\"2022-05-25T16:53:42+00:00\",\"dateModified\":\"2026-02-16T15:37:06+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/iacuc-administrative-review-procedures\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/iacuc-administrative-review-procedures\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/iacuc-administrative-review-procedures\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Compliance\",\"item\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Research Compliance\",\"item\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Animal Care and Use (IACUC)\",\"item\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"IACUC: Procedures and Guidance\",\"item\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/compliance\\\/research-compliance\\\/iacuc\\\/iacuc-procedures-and-guidance\\\/\"},{\"@type\":\"ListItem\",\"position\":6,\"name\":\"Administrative Review Procedures\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/#website\",\"url\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/\",\"name\":\"Research Administration and Compliance\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/research.ncsu.edu\\\/administration\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Administrative Review Procedures - Research Administration and Compliance","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/","og_locale":"en_US","og_type":"article","og_title":"Administrative Review Procedures - Research Administration and Compliance","og_description":"Overview Clarification or minor modifications of proposed changes may be addressed through the administrative review process at the discretion of the veterinarian, IACUC chair and\/or IACUC staff. Any significant concerns…","og_url":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/","og_site_name":"Research Administration and Compliance","article_modified_time":"2026-02-16T15:37:06+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/","url":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/","name":"Administrative Review Procedures - Research Administration and Compliance","isPartOf":{"@id":"https:\/\/research.ncsu.edu\/administration\/#website"},"datePublished":"2022-05-25T16:53:42+00:00","dateModified":"2026-02-16T15:37:06+00:00","breadcrumb":{"@id":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/iacuc-administrative-review-procedures\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/research.ncsu.edu\/administration\/"},{"@type":"ListItem","position":2,"name":"Compliance","item":"https:\/\/research.ncsu.edu\/administration\/compliance\/"},{"@type":"ListItem","position":3,"name":"Research Compliance","item":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/"},{"@type":"ListItem","position":4,"name":"Animal Care and Use (IACUC)","item":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/"},{"@type":"ListItem","position":5,"name":"IACUC: Procedures and Guidance","item":"https:\/\/research.ncsu.edu\/administration\/compliance\/research-compliance\/iacuc\/iacuc-procedures-and-guidance\/"},{"@type":"ListItem","position":6,"name":"Administrative Review Procedures"}]},{"@type":"WebSite","@id":"https:\/\/research.ncsu.edu\/administration\/#website","url":"https:\/\/research.ncsu.edu\/administration\/","name":"Research Administration and Compliance","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/research.ncsu.edu\/administration\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/pages\/1241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/comments?post=1241"}],"version-history":[{"count":6,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/pages\/1241\/revisions"}],"predecessor-version":[{"id":17565,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/pages\/1241\/revisions\/17565"}],"up":[{"embeddable":true,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/pages\/1180"}],"wp:attachment":[{"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/media?parent=1241"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/research.ncsu.edu\/administration\/wp-json\/wp\/v2\/tags?post=1241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}