The mission of this program is to promote innovation and translation of tissue engineered products and regenerative medicine technology.  Multidisciplinary teams focus on novel biomaterials, biomanufacturing, mechanobiology, stem cell technology, tissue-on-chip systems and large animal models to translate basic discoveries into applications of clinical/societal impact.


ligler-150x150Dr. Frances Ligler, Associate Director, CMI- Functional Tissue Engineering

With faculty affiliations both at UNC and NC State in biomedical engineering and nanomedicine, Dr. Fran Ligler will assist CMI members in bridging opportunities across the region in the area of regenerative medicine.  Her personal background includes biochemistry, immunology, diagnostics, biosensors, microfluidics, and organ-on-chip engineering.  She brings long experience in translating innovative concepts to commercial biosensors that produce actionable information at the point of use.



Daniele FTEDr. Michael Daniele & Dr. Fran Ligler, NC State University – “Recreating the Web of Blood Vessels That Keep Human Tissue Alive”

Two FTE Researchers, Dr. Michael Daniele from University of North Carolina-Chapel Hill and Dr. Fran Ligler from North Carolina State University won the Edison Award from the US Naval Research Laboratory for a synthetic micro vessels patent.  They are featured in NC State News.


Dr. Ke Cheng, NC State University – “Spheroid Stem Cell Production Sows Hope for IPF Treatment”




Image by Alice Harvey

Image by Alice Harvey

Dr. Ke Cheng, NC State University – “Synthetic Stem Cells Could Offer Therapeutic Benefits, Reduced Risks”





Hydrogel Picture

Dr. Rohan Shirwaiker – NSF CAREER Award for Dr. Rohan Shirwaiker”