The mission of this program is to promote innovation and translation of tissue engineered products and regenerative medicine technology.  Multidisciplinary teams focus on creation and implementation of novel biomaterials, manufacturing approaches, mechanobiology, stem cell technology,  and large animal models and will work together to translate basic findings into applications of clinical/societal applications.  The program’s mission is also to develop novel genetic approaches to augment the potency of cell therapy and tissue engineering product.



Dr. Ke Cheng and Dr. Binil Starly, Associate Directors, CMI Functional Tissue Engineering

Dr. Ke Cheng is an Associate Professor in the College of Veterinary Medicine, an Associate Professor in the UNC/NCSU Joint Department of Biomedical Engineering and Adjunct Professor in the UNC Eshelman School of Pharmacy and UNC School of Medicine.  With faculty positions both at NC State and UNC, Dr. Cheng will help to bridge opportunities across the region in the area of regenerative medicine.   Dr. Binil Starly is a Chancellor’s Faculty of Excellence Program cluster hire in Regenerative Medicine.  He directs the Data Intensive Manufacturing Laboratory.  As a manufacturing engineer, Dr. Starly will be able to identify, develop and find resources needed to build key platforms to help translate engineered cell, tissue and organ systems to an industrial scale operation.  Such enabling platforms will allow for the automation and standardization of processes involved with either scaling-out or scaling-up regenerative medicine therapies for eventual impact at the bed-side.”



Daniele FTEDr. Michael Daniele & Dr. Fran Ligler, NC State University – “Recreating the Web of Blood Vessels That Keep Human Tissue Alive”

Two FTE Researchers, Dr. Michael Daniele from University of North Carolina-Chapel Hill and Dr. Fran Ligler from North Carolina State University won the Edison Award from the US Naval Research Laboratory for a synthetic micro vessels patent.  They are featured in NC State News.


Dr. Ke Cheng, NC State University – “Spheroid Stem Cell Production Sows Hope for IPF Treatment”




Image by Alice Harvey

Image by Alice Harvey

Dr. Ke Cheng, NC State University – “Synthetic Stem Cells Could Offer Therapeutic Benefits, Reduced Risks”





Hydrogel Picture

Dr. Rohan Shirwaiker – NSF CAREER Award for Dr. Rohan Shirwaiker”