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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20170404T110000
DTEND;TZID=America/New_York:20170404T120000
DTSTAMP:20260504T232859
CREATED:20170318T165210Z
LAST-MODIFIED:20170318T165210Z
UID:1843-1491303600-1491307200@research.ncsu.edu
SUMMARY:Adrienne Roeder: A fluctuation based cell patterning mechanism
DESCRIPTION:Allen Distinguished Microscopy Seminar \nA fluctuation based cell patterning mechanism\nAdrienne Roeder\, Ph.D\,\nWeill Institute for Cell and Molecular Biology\nPlant Biology\nCornell University \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund
URL:https://research.ncsu.edu/cmif/event/adrienne-roeder-a-fluctuation-based-cell-patterning-mechanism/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2017/03/Roeder-April-4-2017.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20170322T090000
DTEND;TZID=America/New_York:20170322T100000
DTSTAMP:20260504T232859
CREATED:20170318T164639Z
LAST-MODIFIED:20170318T164639Z
UID:1841-1490173200-1490176800@research.ncsu.edu
SUMMARY:Diana Fusco: Evolution at the expanding frontier
DESCRIPTION:Allen Distinguished Microscopy Seminar \nEvolution at the expanding  frontier\nDiana Fusco\, Ph.D\,\nLaboratory of Biophysics and Evolutionary Dynamics (Hallatschek Lab)\nUniversity of California\, Berkeley \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund
URL:https://research.ncsu.edu/cmif/event/diana-fusco-evolution-at-the-expanding-frontier/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2017/03/Fusco-March-22-2017.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20170217T120000
DTEND;TZID=America/New_York:20170217T130000
DTSTAMP:20260504T232859
CREATED:20170318T163743Z
LAST-MODIFIED:20170318T163945Z
UID:1837-1487332800-1487336400@research.ncsu.edu
SUMMARY:Elizabeth Hinde: Mapping the diffusive route of transcription factors in live cell nuclear architecture
DESCRIPTION:Allen Distinguished Microscopy Seminar \nMapping the diffusive route of transcription factors in live cell nuclear architecture\nElizabeth Hinde\, Ph.D\,\nSchool of Medical Sciences\nUniversity of New South Wales\nSydney\, Australia \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund
URL:https://research.ncsu.edu/cmif/event/1837/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2017/03/seminar-slide-Elizabeth-Hinde-for-billboard-screen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161109T150000
DTEND;TZID=America/New_York:20161109T160000
DTSTAMP:20260504T232859
CREATED:20161027T184736Z
LAST-MODIFIED:20170318T140703Z
UID:1817-1478703600-1478707200@research.ncsu.edu
SUMMARY:Stefano Di Talia: Time-keeping mechanisms of embryonic cell cycles
DESCRIPTION:Allen Distinguished Microscopy Seminar \nTime-keeping mechanisms of embryonic cell cycles\nStefano Di Talia\, Ph.D\, Assistant Professor\,\nDepartment of Cell Biology\, Duke University Medical Center\, Durham\, NC \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund \nAbstract: Embryonic development requires the accurate regulation of biological events across multiple spatial and temporal scales. In this talk\, I will discuss how the cell cycle is timed accurately during development of Drosophila embryos. I will focus on two separate problems: the synchronization of the early embryonic cell cycles through the rapid propagation of waves of Cdk1 activity and the mechanisms of regulation of the cell cycle during Drosophila gastrulation.
URL:https://research.ncsu.edu/cmif/event/stefano-di-talia-time-keeping-mechanisms-of-embryonic-cell-cycles/
LOCATION:Stephens room\, 3503 Thomas Hall\, NC State University
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/10/seminar-slide-Stefano-Di-Talia-for-billboard-screen-new.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161014T130000
DTEND;TZID=America/New_York:20161014T140000
DTSTAMP:20260504T232859
CREATED:20161003T143450Z
LAST-MODIFIED:20170318T140044Z
UID:1791-1476450000-1476453600@research.ncsu.edu
SUMMARY:Enrico Gratton: Mechanisms of molecular transport in live cells
DESCRIPTION:Allen Distinguished Microscopy Seminar \nMechanism of molecular transport in live cells\nEnrico Gratton\, Ph.D\, Professor\,\nBiomedical Engineering\, Laboratory of Fluorescence Dynamics\nUniversity of California\, Irvine\, CA \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund \nAbstract: The coordination of cell functions requires that molecules move in the cell interior to find their partners. In the cell\, the mechanisms for molecular motion are poorly understood. While in an isotropic fluid diffusion is the default mechanism of motion\, in the cell interior diffusion is hindered by barriers and by transient binding. Also molecules can move by active transport. One universal transport processes which is still debated is the shuttling of molecules between the cell membrane and other locations where the molecules will deliver a signal. Although we have made important progresses in understanding direct motion\, less is understood in regard to paths for diffusion and in general the connectivity of the cell interior. In this talk I will discuss the development of tools that could help us in measuring the path that molecules follow in the cell to reach their target.
URL:https://research.ncsu.edu/cmif/event/enrico-gratton-mechanisms-of-molecular-transport-in-live-cells/
LOCATION:Stephens room\, 3503 Thomas Hall\, NC State University
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/10/seminar-slide-Enrico-Gratton-for-billboard-screen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20160927T160000
DTEND;TZID=America/New_York:20160927T170000
DTSTAMP:20260504T232859
CREATED:20160916T183258Z
LAST-MODIFIED:20161006T230214Z
UID:1782-1474992000-1474995600@research.ncsu.edu
SUMMARY:Charles T. Anderson: Building Biomass: Imaging the Synthesis and Growth Dynamics of Plant Cell Walls
DESCRIPTION:Allen Distinguished Microscopy Seminar \nBuilding Biomass: Imaging the Synthesis and Growth Dynamics of Plant Cell Walls\nCharles T. Anderson\, Ph.D\, Assistant Professor\, Department of Biology\, Penn State University\, PA \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE\, Eastman Chemical University Engagement Fund & Department of Plant and Microbial Biology. \nAbstract: The cell walls of plants are complex\, carbohydrate-based extracellular matrices that determine patterns of plant growth and development. Plant cell walls also embody much of the energy captured during photosynthesis\, making them renewable sources of food\, bioenergy\, and biomaterials. Our group develops and applies advanced imaging methods to investigate how plants initially construct their cell walls and how these walls change during cellular growth. Using quantitative photobleaching and TIRF microscopy\, we are working to count protein subunits in the Cellulose Synthesis Complex\, which produces cellulose\, an abundant but enigmatic polysaccharide component of the plant cell wall. We are also using high-speed confocal microscopy in living plant cells to track the synthesis and reorganization of cellulose. Finally\, we are using super-resolution microscopy to resolve the nanoscale organization of wall-synthesizing machinery\, as well as wall components themselves\, in intact cells\, which will help reveal how plant cell walls confer flexibility and strength to plants.
URL:https://research.ncsu.edu/cmif/event/charles-t-anderson-building-biomass-imaging-the-synthesis-and-growth-dynamics-of-plant-cell-walls/
LOCATION:Stephens room\, 3503 Thomas Hall\, NC State University
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/09/seminar-Charles-Anderson-slide-for-billboard-screen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20160603T120000
DTEND;TZID=America/New_York:20160603T130000
DTSTAMP:20260504T232859
CREATED:20160718T232035Z
LAST-MODIFIED:20161006T230713Z
UID:1561-1464955200-1464958800@research.ncsu.edu
SUMMARY:Karin Schumacher: Live and in color: Improved tools for multi-parameter imaging
DESCRIPTION:Allen Distinguished Microscopy Seminar \nLive and in color: Improved tools for multi-parameter imaging\nKarin Schumacher\, Ph.D\, Professor\,\nPlant Developmental Biology\, Centre for Organismal Studies\nHeidelberg University\, Heidelberg\, Germany \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund \nAbstract: The concentration of two ions\, Ca2+ and H+\, affects almost all biological processes\, and dynamic changes in [Ca2+] and pH are integral components of many signaling pathways. My lab studies the transport machinery that controls cellular pH and Ca2+ -homeostasis and we use genetically-encoded sensors to visualize their spatio-temporal dynamics. In my presentation\, I will cover our recent work on pH-regulation in the plant endomembrane system as well as our attempts to establish transgenic lines that allow monitoring of multiple parameters including pH\, Ca2+\, ROS and ATP.
URL:https://research.ncsu.edu/cmif/event/1561/
LOCATION:NC
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/07/AS_2016_06_03_Karin_Schumacher.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20160427T113000
DTEND;TZID=America/New_York:20160427T123000
DTSTAMP:20260504T232859
CREATED:20160426T151450Z
LAST-MODIFIED:20161006T231344Z
UID:965-1461756600-1461760200@research.ncsu.edu
SUMMARY:Scott Fraser: Sensing and imaging the molecular signatures of embodied cells
DESCRIPTION:Allen Distinguished Microscopy Seminar \nSensing and imaging the molecular signatures of embodied cells\nScott Fraser\, Ph.D\, Provost Professor\, Director of Sciences Initiative\nMolecular and Computational Biology and Biomedical Engineering\nUniversity of Southern California\, Los Angeles\, CA \nSponsored By:\nORIED\, CALS\, COS\, CVM\, COE & Eastman Chemical University Engagement Fund \nAbstract: The challenge of modern embryology is to draw upon the growing body of high-throughput molecular data to better understand the cellular and molecular events underlying embryonic development. This wealth of data now presents the challenge of integrating a working knowledge of how these molecular components\, often present at vanishingly small concentrations\, generate reliable patterns of cell migration and cell differentiation.  In typical cell biology approaches\, cultures of isolated cells have been used to reveal mechanism.  What is needed to understand development is to carry out studies on cells in their normal context interacting with other cells and signals in the intact embryo.  \nImaging techniques are challenged by major tradeoffs between spatial resolution\, temporal resolution\, and the limited photon budget.  We are attempting to advance this tradeoff by constructing faster and more efficient light sheet microscopes that maintain subcellular resolution.  Our two-photon light-sheet microscope combines the deep penetration of two-photon microscopy and the speed of light sheet microscopy to generate images with more than ten-fold improved imaging speed and sensitivity.  As with other light sheet technologies\, the collection of an entire 2-D optical section in parallel offers dramatically speeds acquisition rates.  Two-photon light sheet microscopy is far less subject to light scattering\, permitting subcellular resolution to be maintained far better than conventional light sheet microscopes.  The combination of attributes permits cell and molecular imaging with sufficient speed and resolution to generate unambiguous tracing of cells and signals in intact systems.   \nMultispectral imaging offers the chance of asking multiple questions of the same embodied cells.  Multiplex analyses permit the variance and the “noise” in a system to be exploited by asking about the analytes that co-vary with a selected gene product.  These approaches allow straightforward prediction of draft gene regulatory networks. \nIn parallel\, label-free approaches offer an important approach for molecular sensing\, but the low concentrations and low sensitivity of the techniques can make single cell approaches challenging.  We have refined a new technology for enhancing these signals and have achieved gains that make the analysis of single cells possible.
URL:https://research.ncsu.edu/cmif/event/sensing-and-imaging-the-molecular-signatures-of-embodied-cells/
LOCATION:Hunt Library Auditorium\, 1070 Partners Way\, Raleigh\, NC\, 27606\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/04/seminar-4-27-16.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20160330T130000
DTEND;TZID=America/New_York:20160330T140000
DTSTAMP:20260504T232859
CREATED:20160322T142045Z
LAST-MODIFIED:20161006T231234Z
UID:665-1459342800-1459346400@research.ncsu.edu
SUMMARY:Spencer Smith: New imaging technology for watching the brain in action at cellular resolution.
DESCRIPTION:Allen Distinguished Microscopy Seminar \nNew imaging technology for watching the brain in action at cellular resolution.\nSpencer Smith\, Ph.D\, Assistant Professor \nNeuroscience Center\, UNC Chapel Hill \nSponsored By: \nORIED\, CALS\, COS\, CVM\, COE and Eastman Chemical University Engagement Fund \nAbstract: Microscopy can capture biological dynamics at high resolution\, but only over a restricted field of view. This limitation is particularly crippling for neuroscience. The restricted field of view prevents the imaging of interactions between neurons in different brain regions. To reveal these dynamics\, my lab is developing new multiphoton imaging systems. These systems resolve 50-100 fold more data per field of view than conventional microscopes\, and use multiplexed imaging beams to simultaneously sample neurons in different parts of the brain. With this new technology\, we are mapping neuronal dynamics at ever growing scales\, and learning how the different regions of the brain work together to encode stimuli and drive behavior.
URL:https://research.ncsu.edu/cmif/event/allen-distinguished-microscopy-seminar-spencer-smith-ph-d/
LOCATION:CVM Research Bldg. RB101\, 1051 William Moore Drive\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2016_03_30_Spencer_Smith.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20160316T180000
DTEND;TZID=America/New_York:20160316T200000
DTSTAMP:20260504T232859
CREATED:20160418T144130Z
LAST-MODIFIED:20160515T203724Z
UID:830-1458151200-1458158400@research.ncsu.edu
SUMMARY:Exploring the Micro-World: Where science meets art
DESCRIPTION:Eva Johannes\, Director Cellular & Molecular Imaging Facility \nOffice of Research\, Innovation & Economic Development (ORIED)
URL:https://research.ncsu.edu/cmif/event/exploring-the-micro-world-where-science-meets-art/
LOCATION:Crafts Center\, Thompsons Hall\, 210 Jensen Dr.\, Raleigh\, NC\, United States
CATEGORIES:Outreach
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/04/presentation_crafts_center_March_16_2016-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20151104T153000
DTEND;TZID=America/New_York:20151104T163000
DTSTAMP:20260504T232859
CREATED:20160322T143650Z
LAST-MODIFIED:20160718T230140Z
UID:669-1446651000-1446654600@research.ncsu.edu
SUMMARY:Thomas Finger: 3D Reconstruction of Taste Buds
DESCRIPTION:Allen Distinguished Microscopy Seminar & W. M Keck Center co-sponsored Seminar \n3D Reconstruction of Taste Buds Ultrastructure show Chemical Synapses Lacking Synaptic Vesicles\nThomas E. Finger\, Ph.D\, Professor \nRocky Mountain Taste & Smell Center\nDept. Cell & Developmental Biology\nUniversity of Colorado School of Medicine \nSponsored by: \nW. M. Keck Center\, ORIED\, Eastman Chemical University Engagement Fund\, CALS\, COS\, CVM and COE.
URL:https://research.ncsu.edu/cmif/event/3d-reconstruction-of-taste-buds/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2015_11_04_Thomas_Finger.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20150422T120000
DTEND;TZID=America/New_York:20150422T130000
DTSTAMP:20260504T232859
CREATED:20160324T152514Z
LAST-MODIFIED:20160718T230254Z
UID:775-1429704000-1429707600@research.ncsu.edu
SUMMARY:Jason Haugh: Directed migration of mesenchymal cells: Where signaling and the cytoskeleton meet
DESCRIPTION:Allen Distinguished Microscopy Seminar \nDirected migration of mesenchymal cells: Where signaling and the cytoskeleton meet\nJason Haugh\, Ph.D\, Professor\nChemical & Biomolecular Engineering\nCollege of Engineering\, NCSU \nSponsored By: \nORIED\, CALS\, COS\, CVM\, COE and Eastman Chemical University Engagement Fund
URL:https://research.ncsu.edu/cmif/event/directed-migration-of-mesenchymal-cells-where-signaling-and-the-cytoskeleton-meet/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2015_04_22_Jason_Haugh.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20141105T160000
DTEND;TZID=America/New_York:20141105T170000
DTSTAMP:20260504T232859
CREATED:20160324T153026Z
LAST-MODIFIED:20161006T232025Z
UID:785-1415203200-1415206800@research.ncsu.edu
SUMMARY:Diego Bohorquez: Illuminating the neural circuitry of gut feelings
DESCRIPTION:Allen Distinguished Microscopy Seminar \nIlluminating the neural circuitry of gut feelings\nDiego V. Bohorquez\, Postdoctoral Fellow\nDuke Medicine Center\nDuke University\, NC \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE \nAbstract: Our brain is fed with sensory information from food in our gut through specialized biosensors called enteroendocrine cells. For long these cells have been assumed to communicate with nerves indirectly through hormones. This is mainly because enteroendocrine cells are scattered throughout the intestinal epithelium and difficult to identify. Therefore\, a complete description of their anatomy is lacking. Using several microscopy techniques\, including correlative confocal microscopy with 3D electron microscopy\, we have unveil a physical connection between enteroendocrine cells and sensory nerves innervating the small intestine and colon. This is a novel neurocircuit and constitutes a potential first point of sensory integration between food in our intestines and satiety in our brains.
URL:https://research.ncsu.edu/cmif/event/illuminating-the-neural-circuitry-of-gut-feelings/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_11_05_Diego_Bohorquez.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20141022T160000
DTEND;TZID=America/New_York:20141022T170000
DTSTAMP:20260504T232859
CREATED:20160324T153637Z
LAST-MODIFIED:20160718T230433Z
UID:786-1413993600-1413997200@research.ncsu.edu
SUMMARY:David Ehrhardt: Mechanisms of dynamic molecular organization at the cell cortex of higher plants
DESCRIPTION:Allen Distinguished Microscopy Seminar \nMechanisms of dynamic molecular organization at the cell cortex of higher plants\nDavid Ehrhardt\, Ph.D\, Associate Professor \nDepartment of Plant Biology\nCarnegie Institution for Science (Stanford\, CA) \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE.
URL:https://research.ncsu.edu/cmif/event/mechanisms-of-dynamic-molecular-organization-at-the-cell-cortex-of-higher-plants/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_10_22_David-Ehrhardt.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20140925T153000
DTEND;TZID=America/New_York:20140925T163000
DTSTAMP:20260504T232859
CREATED:20160324T154124Z
LAST-MODIFIED:20160718T230526Z
UID:787-1411659000-1411662600@research.ncsu.edu
SUMMARY:Ann-Shyn Chiang: Solving the Fly Brain
DESCRIPTION:Allen Distinguished Microscopy & W. M. Keck Center co-sponsored Seminar \nSolving the Fly Brain\nAnn-Shyn Chiang\, Ph.D\, Tsing Hua Chair Professor & Director Brain Research Center\nNational Tsing Hua University\, Taiwan\nFaculty Kavli Institute for Brain and Mind\nUniversity of California\, San Diego \nSponsored By: \nORIED\, CALS\, COS\, CVM\, COE and W. M. Keck Center.
URL:https://research.ncsu.edu/cmif/event/solving-the-fly-brain/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_09_25_Ann-Shyn_Chiang.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20140623T163000
DTEND;TZID=America/New_York:20140623T173000
DTSTAMP:20260504T232859
CREATED:20160324T154553Z
LAST-MODIFIED:20161006T232600Z
UID:788-1403541000-1403544600@research.ncsu.edu
SUMMARY:David Piston: Imaging the molecular mechanisms of pancreatic hormone secretion
DESCRIPTION:Allen Distinguished Microscopy Seminar \nImaging the molecular mechanisms of pancreatic hormone secretion\nDavid Piston\, Ph.D\, Professor of Department of Molecular Physiology and Biophysics\, Director Biophotonics Institute\nVanderbilt University School of Medicine (Nashville\, TN) \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE. \nAbstract: Research in Dr. Piston’s lab focuses on molecular events involved in glucose metabolism and insulin secretion in beta cells within intact functioning pancreatic islets. They have developed unique\, state-of-the-art fluorescence imaging methods to assay the response at various points along the glucose transduction pathway. The quantitative microscopy is combined with standard biochemical and molecular biological techniques to obtain unique information that bridges the gap between the known details of the glucose transduction pathway in individual beta cells and the overall glucose response of a whole islet.
URL:https://research.ncsu.edu/cmif/event/imaging-the-molecular-mechanisms-of-pancreatic-hormone-secretion/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_07_23_David_Piston.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20140528T160000
DTEND;TZID=America/New_York:20140528T170000
DTSTAMP:20260504T232859
CREATED:20160324T155011Z
LAST-MODIFIED:20161006T232722Z
UID:789-1401292800-1401296400@research.ncsu.edu
SUMMARY:Stephanie Gupton: TRIM9 coordinates cytoskeletal dynamics and vesicle trafficking in developing neurons
DESCRIPTION:Allen Distinguished Microscopy Seminar \nTRIM9 coordinates cytoskeletal dynamics and vesicle trafficking in developing neurons\nStephanie Gupton\, Ph.D\, Assistant Professor \nDepartment of Cell Biology & Physiology\, UNC\nUNC Neuroscience Center\nUNC Lineberger Comprehensive Cancer Center \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE. \nAbstract: We have recently identified the E3 ubiquitin ligase as a critical catalytic component downstream of the axon guidance cue Netrin during neuronal development. TRIM9 interacts with the Netrin receptor DCC\, regulators of the actin cytoskeleton\, and vesicle trafficking machinery.  Using biochemical techniques\, high resolution microscopy\, and mouse models we show that TRIM9 controls vesicle exocytosis\, filopodia formation and axon guidance and branching.
URL:https://research.ncsu.edu/cmif/event/trim9-coordinates-cytoskeletal-dynamics-and-vesicle-trafficking-in-developing-neurons/
LOCATION:Thomas Hall – Stephens Room\, 112 Derieux Pl.\, Raleigh\, NC\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_05_28_Stephanie_Gupton.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20140423T040000
DTEND;TZID=America/New_York:20140423T170000
DTSTAMP:20260504T232859
CREATED:20160324T155537Z
LAST-MODIFIED:20161006T233209Z
UID:790-1398225600-1398272400@research.ncsu.edu
SUMMARY:Keith Weninger: Connecting protein conformational dynamics with function using single molecule fluorescence microscopy
DESCRIPTION:Allen Distinguished Microscopy Seminar \nConnecting protein conformational dynamics with function using single molecule fluorescence microscopy\nKeith Weninger\, Ph.D\, Assistant Professor \nUniversity Faculty Scholar\nDepartment of Physics\, College of Sciences\, NCSU \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE. \nAbstract: Observing single molecules allows discovery of properties that are typically hidden by averaging over the large number of unsynchronized molecules typical of biological samples. Single molecule fluorescence resonance energy transfer is a method that allows real-time observation of protein and DNA conformational changes with nanometer resolution. I will describe our applications of single molecule fluorescence microscopy to studies of proteins involved in several phenomena including DNA mismatch repair\, neurotransmitter release and cancer related processes.
URL:https://research.ncsu.edu/cmif/event/connecting-protein-conformational-dynamics-with-function-using-single-molecule-fluorescence-microscopy/
LOCATION:D.H. Hill Library NCSU\, 2 W Broughton Dr\,\, Raleigh\, NC\, 27695\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_04_23_Keith_Weninger.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20140326T160000
DTEND;TZID=America/New_York:20140326T170000
DTSTAMP:20260504T232859
CREATED:20160324T155859Z
LAST-MODIFIED:20160718T230851Z
UID:792-1395849600-1395853200@research.ncsu.edu
SUMMARY:Edward Salmon: Super-resolution fluorescence microscopy of human kinetochore protein architecture and function
DESCRIPTION:Allen Distinguished Microscopy Seminar \nSuper-resolution fluorescence microscopy of human kinetochore protein architecture and function\nEdward D. Salmon\, Ph.D\, James Larking and Iona Mae Ballou \nUNC Distinguished Professor\nMember American Academy of Arts and Sciences \nSponsored By: \nORIED\, CALS\, COS\, CVM & COE.
URL:https://research.ncsu.edu/cmif/event/super-resolution-fluorescence-microscopy-of-human-kinetochore-protein-architecture-and-function/
LOCATION:D.H. Hill Library NCSU\, 2 W Broughton Dr\,\, Raleigh\, NC\, 27695\, United States
CATEGORIES:Allen Distinguished Microscopy Seminar
ATTACH;FMTTYPE=image/jpeg:https://research.ncsu.edu/cmif/files/2016/03/AS_2014_03_26_Edward_Salmon.jpg
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END:VCALENDAR