More than 100 companies trace their beginnings to NC State, including multinational corporations like SAS Institute and CREE. NC State’s startups, which play an important role in strengthening the economy of North Carolina and providing solutions that improve the lives of our citizens, are listed on this page.





410 Medical Innovations

410 Medical Innovations is working to commercialize a fluid delivery method for patients during emergency situations, resulting in improvement of survival rates and quality of life for patients.


Agile Sciences, Inc.

Agile Sciences was founded in 2007 to provide commercial solutions to industries plagued by the effects of biofilms.



AgRenaissance Software, LLC

AgRenaissance Software’s primary product is FieldX™, an agricultural record-keeping tool for producers, agronomists, and applicators. The FieldX software suite is an easy-to-use cloud-based and mobile system to record and synchronize agricultural data.



Air Glow has developed a large area, high density, non-equilibrium atmospheric pressure plasma source based on a coaxially-driven VHF system. The novel plasma technology could be applied to chemical abatement, biological remediation, and surface treatments such as deposition, etching, and activation. The seed stage company has built and characterized a prototype, and a provisional patent has been filed.



Allasso Industries, Inc.

Allasso Industries was formed and organized around a strategic plan to identify, evaluate, develop, and commercialize emerging technologies that provide customers with innovative and cost effective solutions to material production and performance challenges.


AlphaVax, Inc.

AlphaVax is developing a new vaccine technology with broad applications against infectious disease, cancer and biodefense threats which has the potential to redefine vaccines and the role they play in medicine.

Applied Combustion Technologies


ArboVax, Inc.

ARBOVAX™, Inc. has a unique technology that modifies arthropod-borne viruses (arboviruses) making them unable to replicate in mammalian cells. Arbovax will leverage this technology through partnerships with pharmaceutical companies to facilitate the development of a portfolio of new and improved human vaccines against the worldwide threat of arthropod-borne diseases.



ArrayXpress presents the microarray industry’s first complete, end-to-end custom solution for customers at all stages of research.




Aseptia was created in 2006 and is in the business of commercializing technologies in the food industry using novel technologies licensed from NC State. These technologies enable the production of novel food products with superior nutrition and a high level of food safety.



Atmospheric Plasma Solutions, Inc. (AP Solutions)

Part design firm and part OEM, AP Solutions has developed a unique portfolio of products and applications that have brought cutting-edge Atmospheric Plasma Technology to industrial and research organizations across the world.




Atomix LLC

Doing business as “2DLayer”, Atomix produces thin, sheet material for use in the semiconductor industry. Its technology allows for controlled, scalable synthesis of large-area, high quality, atomically thin semiconductor materials in cost-effective ways.



Augment Medical

Augment Medical is a small, biomedical engineering firm that is focused on providing innovative solutions to the augmentative and alternative communications industry.





Benanova, Inc.

BENANOVA has developed a cost-efficient, environmentally benign particle system (EbNPs) made of natural materials, which can leverage the functional properties of bioactive agents. This innovative, patent-pending technology can facilitate the development of highly efficient, application-customized and environmentally benign replacements for silver nanoparticle antimicrobials.


Biocentric Media

BioCentric Media, LLC is an educational application development company specializing in secondary and post-secondary life science content.



BioMarck Pharmaceuticals, Ltd.

BioMarck Pharmaceuticals, Ltd. is a biopharmaceutical company dedicated to the discovery and development of new drugs for the treatment of pulmonary diseases and disorders associated with over-secretion of mucus and inflammation.


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BreStem, Inc.

BreStem is working to fight pulmonary fibrosis through stem cell therapy for lung regeneration. Their Autologous Lung Spheroid Cells (LSC) Therapy provides a novel process to isolate and expand a novel source of resident lung progenitors for cell-based lung regeneration, and has the potential to provide promising therapeutic treatments for pulmonary diseases involving fibrosis, degeneration, and inflammation.



BioResource International, Inc.

BioResource International (BRI) is a North Carolina based biotechnology company focused on the discovery and development of enzymes to enhance and protect animal and human health.





CellSentry, Inc.

CellSentry has created a new trust verification security platform for mobile phones and other IT platforms.


Clave Biodesign, Inc.

Clave BioDesign is focused on developing technology that enables more specific, less toxic, and less immunogenic targeting of tumor cells using cell-specific peptides. These peptides can be used for therapeutic purposes related to cancer, CVD, and ophthalmology as well as for diagnostic purposes related to imaging and biomarkers.



CompletErgo, LLC.

CompletErgo is the complete solution for managing a company’s office ergonomics program. It’s a web-based software solution that includes an online training module, an employee self-assessment feature, and a data management system.



Cree, Inc.

Cree, Inc. is a market-leading innovator and manufacturer of semiconductors that enhance the value of LED solid-state lighting, power and communications products by significantly increasing their energy performance. Key to Cree’s market advantage is unrivaled materials expertise in silicon carbide (SiC) with gallium nitride (GaN) to deliver chips and packaged devices that can handle more power in a smaller space while producing less heat than other available technologies, materials and products.




Custom Nano, Inc.

Custom Nano, Inc. manufactures gold nano-rods (GNRs) in specific lengths and aspect ratios that have desirable surface plasmon resonances. Their patented process allows synthesis of uniform, concentrated, and stable GNRs on large scales, which can be used in targeted therapies, biosensors, biomedical stents, catalysis, and security materials.





Eagle Power Technologies 

Eagle Power Technologies is developing 99% efficient motors and generators for aerospace applications.


EcoPRT represents a new and revolutionary way to think about transportation in urban and suburban environments. EcoPRT hopes to solve traffic congestion through its revolutionary public transportation system that is lightweight and low-cost with the smallest possible footprint that can be installed on existing rights-of-way.



Empire Foods

Empire Foods is a food processing company that uses technology licensed from NC State to preserve fresh, local produce, retaining up to 98 percent of their antioxidants and nutrients, making them shelf-stable for up to a year without refrigeration. There are no added sugars, preservatives or artificial flavorings.




eSionic is passionate about solving problems at energy electronics nexus. eSionic is enabling devices and systems that consume less materials, generate less waste, have longer life, operate with higher reliability, use less energy, integrate seamlessly, operate more efficiently and cost less. eSionic is doing this through the use of proprietary molecular systems.




Fathom Science

Fathom Science delivers high-resolution, high-fidelity marine environment analytics. Our industry-leading oceanographic and meteorological analyses fill gaps in existing data sets, predict future conditions, and deliver precise information to sectors such as energy, fishing, risk assessment, severe weather, ship routing, tourism, and water quality.




Galaxy Diagnostics, Inc.

Galaxy Diagnostics combines a patented enrichment media with state-of-the-art molecular detection methods to significantly increase the odds of detecting the presence of Bartonella species bacteria in a given sample.


GridBridge, Inc.

GridBridge was formed in order to offer advanced technology solutions that will modernize the electrical grid. With partner electric utilities, GridBridge will introduce and implement revolutionary products that enable the adoption of green technology, optimize electricity flow on the grid, minimize costly capital-intensive overhauls, and ensure end-user satisfaction.





Harrison Analytic Technologies, LLC

Harrison Analytic Technologies LLC is developing the Battery Parameters/SOC/SOH Co-estimation technology to provide accurate State of Charge (SOC) and State of Health (SOH) estimations for rechargeable batteries in order to make Battery Management Systems (BMS) smarter. HAT seeks to offer better accuracy and reliability, especially in Electric Vehicle (EV) industry.


HexaTech, Inc.

HexaTech Inc. is a privately held company founded in 2001, focused on developing and producing single crystalline aluminum nitride (AlN) substrates for high performance electronic and optoelectronic devices.



HueMetrix, Inc.

HueMetrix is located in Raleigh, North Carolina, and is dedicated to making ‘Right First Time’ dyeing a reality through the development, production, and service of real-time dye exhaustion optimization and adaptive color control systems for textile laboratory and production environments.






ImagineOptix is commercializing a patented thin-film polarizing beamsplitter technology called HoloBrightTM.


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Infinity Gates

Infinity Gates is developing hardware to support artificial intelligence and Internet of Things through utilization of nonlinear dynamics and chaos theory.


InsightFinder, Inc.

InsightFinder is a cloud monitoring and system analytics tool that provides smart monitoring and predictive analysis services based on cutting-edge unsupervised machine learning technologies.


Intelligent Campus Solutions, Inc.

Livitae is designed for today’s mobile students, administrators, counselors and parents to navigate the treacherous journey from enrollment to employment with ease.

Ironwood Material Science, Inc.

Ironwood Material Science, Inc. is a medical device company focused on developing novel materials for use as bone cement and synthetic bone in dental and orthopedic applications. This technology is the result of collaborative research between NC State and UNC Chapel Hill.


International Technology Systems Transfer (ITST), LLC

Seeking to commercialize a novel method of carbon capture using advanced materials.





Kyma Technologies, Inc.

Kyma produces and markets semi-conductor products related to gallium nitride (GaN), aluminum nitride (AlN), and other group III-nitride based alloys. The properties of these new materials promise to revolutionize numerous industries, particularly solid state lighting, power switching, and high temperature electronics.



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Lachancea LLC

Lachancea provides unique species of yeast to the brewing industry for brewing applications. Utilizing a species of yeast initially found in paper wasps and bumblebees and never before used in commercial beer brewing, Lachancea allows for the production of unique beers without bacteria and in record time.




Learning Sciences Group

Learning Sciences Group is a company that produces math-based software for K-12 school children. Their product Math-Mapper™ is an intuitive tool that shows teachers and students what needs to be learned and assesses and provides feedback on students’ progress over time.



LipoScience, Inc.

The LipoScience NMR LipoProfile® test is an advanced cardiovascular diagnostic test that uses nuclear magnetic resonance (NMR) spectroscopy to uniquely provide rapid, simultaneous and direct measurement of LDL particle number and size of LDL particles, as well as direct measurement of HDL and VLDL subclasses.



Liquidia Technologies, Inc.

Liquidia Technologies enables high-value products in the life sciences and Materials Science through its innovative PRINT platform. This platform allows the company to design and manufacture precise nanoscale features in the form of nanoparticles and patterned films.



Locus Biosciences, Inc.

Locus Biosciences is an emerging biotechnology company focused on the discovery and development of a next generation CRISPR-Cas platform for Programmed Cell Death. Locus is advancing its platform to create therapeutics for critical disease areas ranging from resistant bacterial infections to the microbiome.


Lumeova, Inc.

A resident of the NC State technology Incubator, Lumeova is focused on the development of advanced communications solutions.





Lupine Materials and Technology

Lupine Materials and Technology (LMT) offers a broad range of research and development on magnetic and superconducting materials, as well as a wide range of processing and system integrations for biferroics, RF components and optical fibers as quench detection sensors.





MAA Laboratories, Inc.

Discovering, developing, and commercializing novel oral medicines for Alzheimer and Migraines.



Mlinzï Vaccines, LLC

Mlinzi Vaccines is a startup project focused on commercializing a salmonella vaccine platform whose first product will be a salmonella vaccine for poultry, which will prevent foodborne diseases by attacking the bacteria at the source, making poultry and eggs safer for human consumption.



Multiform Harvest

Multiform Harvest Inc. is a private company based in Seattle, Washington, which has developed a patented technology that recovers excess phosphorus and nitrogen from wastewater and converts it into a premium, slow-release fertilizer. The technology allows wastewater treatment plants to meet nutrient discharge limits more cost-effectively than other technologies, and provides a sustainable, domestic supply of a diminishing world resource – phosphorus.






NanoVector is an early stage therapeutic drug company commercializing a patent pending nanoparticle targeted drug delivery system developed at NC State.


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NExS Software, LLC

NExS Software is developing a family of products aimed at improving business operations and productivity. Their core technology is the NExS spreadsheet engine, a highly optimized spreadsheet processing engine that interprets and processes spreadsheet formulas. This technology will allow customers to highly leverage their existing spreadsheet portfolios and knowledge base to increase productivity while significantly lowering development time and effort.



Nine Oak Media, LLC.

Nine Oak Media, LLC. is a multimedia educational applications company. Their first application, “Trot to Trophy” is a mobile game with educational intent, encouraging players to learn and master the ways of the equine world that is expected to be available on the Apple platform in September 2014.


NIRvana Sciences, Inc.

NIRvana Sciences is a technology development company focused on fluorescent dyes with ultra-narrow spectrums for the advancement of multiplexing applications in medical diagnostics and imaging markets. The company has an experienced early stage venture team and is located at First Flight Venture Center in RTP, North Carolina. It is a spin-out from the Department of Chemistry at NC State.



Nitronex Corporation

Located near North Carolina’s Research Triangle Park, Nitronex creates radio frequency (RF) power transistors utilizing the world’s only commercial-grade gallium nitride (GaN) RF power semiconductor process capable of revolutionizing the performance, cost and use of mobile communications networks.



NoviSystems, Inc.

NoviSystems builds AI systems to enable business leaders to drive effective business decisions. Their NoviLens AI Appliance product allows users to explore in real time both textual and numerical data from multiple sources in a decision management framework, allowing them to leverage their data confidently and economically to improve the efficiency of their organizations. Solutions are typically built in minutes not months, and there is no need for programming or data science expertise to use the system.



Novocor Medical SystEMS, Inc.

Novocor Medical Systems provides solutions that help Emergency Medical Service first responders save lives. Their patent pending product, HypoCore, is an innovative rapid chilling device for inducing therapeutic hypothermia in cardiac arrest, traumatic brain injury, heat stroke and heavily concussed patients to markedly improve patient survival rate. HypoCore is ready on demand. It is easily stored in ambulances, fire trucks, and helicopters. It does not require external power and is compatible with standard medical equipment.





Origen Therapeutics, Inc.

Origen Therapeutics is a biotechnology company developing product opportunities arising from the emerging field of avian transgenic animal technology. The company’s mission is to become the leading developer of a novel class human immunotherapeutics known as fully human sequence polyclonal antibodies.



Ovation Biotech, Inc.

Ovation Biotech, Inc. is an early stage company producing renewable alkanes from recycled, waste and non food raw materials such as used cooking oil. Renewable alkanes are a direct replacement for petroleum alkanes, a primary ingredient in fuels and industrial products.





People-First Tourism Inc.

People-First Tourism is a marketplace for buying and selling genuine tourism experiences. This project links entrepreneurs trying to pursue dignified and sustainable livelihoods through tourism with adventurous and conscientious tourists interested in unique off the beaten path experiences and in making positive impacts on the communities they visit.


Permafuels, Inc

Permafuels, Inc. is a technology start-up that provides engineering solutions for sustainable energy, with a focus on the development of biofuel production processes.  We are currently seeking partners for a pilot production plant capable of transforming biological fats and oils to drop-in replacements for hydrocarbon fuels, including gasoline, diesel, and jet fuel.


Physcient, Inc.

Physcient combines modern automation and unique knowledge of surgical biomechanics to develop minimally traumatic surgical devices.  Physcient’s first product will be an instrument called a “thoracic retractor” used to gain surgical access for open-chest surgical procedures — lung and heart surgeries. Rather than develop complicated minimally invasive approaches, Physcient has demonstrated in pre-clinical trials that many of the advantages of minimally invasive surgeries (less pain, less trauma, improved respiratory function) can be delivered by improving the thoracic retractor.


Polymer Braille, Inc.

Polymer Braille is developing a tablet e-reader for the blind using a new tactile display generated from a combination of micro-robotics and electroactive polymers. This new device will offer a tremendous advancement in Braille readers, including the creation of multi-line performance capabilities and offers other tactile communication capabilities.


Precision Diagnostics, Inc.

Precision Diagnostics, Inc. was formed for the sales and distribution of medical devices and diagnostic testing.  Precision Diagnostics has now licensed through NC State University the rights to manufacture and distribute PrecisiBand products.


Premitec, Inc.

With a mission to assist companies in new product development by providing complete microfabrication design, development, prototyping, testing, and initial manufacturing of advanced medical sensor systems and devices based on micro and nano-technologies, Premitec, Inc. was Founded in July of 1999 as a spin-off from the Biomedical Microsensors Laboratory (BMMSL) and the Center for Advanced Manufacturing Processes and Materials (CAMP-M) at NC State.


Q-Carbon LLC



Quantum Logic Devices

Quantum Logic Devices was incorporated in September 2000 to provide faster, smarter, less expensive tools for drug research and medical diagnostic applications. Over the last six years the company has developed its core technology, based on single electron devices, into a platform with the ability to electronically detect single molecules of DNA or a single antigen in a simple, rapid, and highly specific assay without fluorescent labels.






RiboWiz Scientific, Inc.

RiboWiz offers customized services and web-based software licensing to maximize recombinant protein production, e.g. biologics, vaccines, antibodies, enzymes, and organic pesticides, for life science companies. RiboWiz’s mission is to help clients successfully produce high-value, complicated recombinant proteins faster through novel gene design manipulations for the advancement of medicine and biotechnology.


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Rise Therapeutics

Rise Therapeutics is focused on developing targeted immunological-based biologics using a unique and proprietary oral delivery platform.



RJL Interactive, LLC

“Drug2Market” is a computer simulation gaming program that allows users to select a biological drug and then make all the decisions required to commercialize the drug including process development, manufacture of clinical trial material, clinical trials, outsourcing, etc.



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Sanctuary Systems LLC

Sanctuary Systems produces environmentally-conscious products based on fiber technology. Focusing on non-woven fabric and fiber production that is both economical and environmental, its products include degradable bags, durable high-tech wipes, and filtration media.




Scientific Organizational Solutions, LLC

Scientific Organizational Solutions, LLC was founded as a collaboration among Drs. Bart Craig, Adam Meade, and Mark Wilson. After years of working as faculty colleagues in the doctoral Industrial/Organizational Psychology program at NC State, the three formed SOS, LLC to collaborate in organizational settings. Scientific Organizational Solutions, LLC is currently pursuing the commercialization of a novel psychometric personality testing software application called PerSight™ that is more difficult to fake, and can be offered much faster.



Sentinel Biomedical

Sentinel Biomedical Inc. is developing an early bladder cancer detection system for dogs that is also aimed at helping humans. Their research is focused on investigating the molecular basis of canine cancers and the identification of potential environmental influences that may be shared with human cancers.



SinnovaTek specializes in the implementation of advanced thermal and continuous flow pasteurization and sterilization systems generating shelf stable products, requiring no freezing or refrigeration during transport, storage and distribution.



Sirga Advanced Biopharma

Sirga Advanced Biopharma, SirgaAB, is an early-phase drug discovery company with unique experience, and proprietary technologies and targets. SirgaAB focuses on novel targets of drug -resistant pathogens (bacterial, fungal and viral) and human diseases in developing new medicines for difficult human health problems. SirgaAB specializes in targets that are difficult for the pathogenic organism to alter, thus reducing the potential for further drug resistance, and in targets that alter human gene expression.




Smart Material Solutions, Inc.

Smart Material Solutions, Inc., expertise includes smart materials, prototype development, and precision engineering. Their goal is to develop and commercialize Nanocoining – a scalable and cost-effective nanofabrication process that can create anti-reflective and self-cleaning surfaces for windows, solar cells, or electronics displays.




SolarAmp LLC is an R&D company focused on renewable energy solutions. Specifically, SolarAmp is focused on providing a very cost-effective photovoltaic (PV) module for solar cells.



Statera Environmental Inc. 

Statera offers a unique passive sampling exposure assessment technology that provides an unprecedented comprehensive picture of chemical exposure. Statera also provides related professional services needed to properly design exposure and risk assessment studies, analyze and interpret chemical and toxicological data, and make informed decisions that are scientifically defensible.




STEM Teacher Learning 

STEM Teacher Learning provides professional development for Technology Education teachers through the use of cyberinfrastructure and the world wide web to significantly enhance the delivery and quality of professional development for grades 6-12 engineering, technology, and design educators.






Tethis, Inc., a Raleigh-based startup materials company, is seeking to commercialize a groundbreaking new material that has the ability to chemically remove salt and minerals from industrial and naturally occurring brines. The material, Tethex, is a biodegradable foam licensed from NC State that binds with dissolved salts, minerals, and other materials, allowing them to be physically removed from waste water.


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Teveri’s wires and proprietary interconnects allow seamless integration of electronics in athletic apparel. Without conductive coatings, wires, or bulky electronics, these systems are reliable, stretchable, and washable.


TextileScents, LLC

Seeking to commercialize novel technologies for infusing aromas into textile products.



Thermalytics, LLC

ThermaLytics is a technology company dedicated to development, integration and commercialization of innovative, multi-functional and robust devices, instruments, software and logistics for measurement, monitoring and validation of continuous flow processes in food, bioprocessing and other industries, with a special focus on monitoring continuous flow of multiphase and solid particulate-containing products.




Thermo-Flex Technologies, Inc.

Thermo-Flex Technologies has commercialized a Thermoelectric Textile that harnesses wasted heat to generate electricity, improving energy efficiency and realizing cost savings. Compared to current thermoelectric technologies, the Thermoelectric Textile can universally integrate with current industrial or commercial sources of waste heat and is also economical with current textile and printing manufacturing.



Third Floor Materials

Third Floor Materials is developing infrared detector technologies for the defense and consumer markets.


Trana Discovery, Inc.

Trana Discovery is a drug discovery company whose technology identifies compounds that interrupt the lifecycle of pathogens through a novel mechanism of action – the inhibition of transfer RNA (tRNA). The company enables exclusive rights to new classes of drugs used to treat serious bacterial, fungal and viral infectious diseases.


TriboFilm Research, Inc.

TriboFilm Research, Inc. based in Raleigh, NC, is a one-of-a-kind entrepreneurial research incubator with material scientists, chemists and engineers from diverse industries including medical devices, semiconductor materials processing, and polymer & textile chemistry.






Vadum, Inc.

Vadum, Inc. is an RF systems engineering and design company that provides innovative solutions in advancing the state-of-the-art in the Radio Frequency Measurement and Signatures Intelligence (RF MASINT) discipline.



VeriQ, Inc.

(Proteome Sciences PLC)

It is estimated that many of the oligonucleotides used to manufacture microarrays suffer from quality control issues, resulting in unreliable performance.  VeriQ Inc. is developing technology for quality control applications in the synthetic oligonucleotide production of RNA, DNA, RNAi, siRNA and microarray technology.



VitalFlo is a digital health company redefining the standard of care for asthma
management. VitalFlo’s low cost, handheld spirometer provides population-level insights to providers, diagnostic support to physicians, and actionable recommendations to patients.






WebAssign unlocks the door to a new way of teaching – to a classroom without walls, where time is no longer a boundary and record keeping is not a constraint. Our unparalleled homework delivery system harnesses the power of the Internet and puts it to work for instructors.


Wright Foods

Wright Foods is a state-of-the-art aseptic food processing company capable of creating food products unmatched by any other food producer in the world. As the technology leader in shelf-stable food processing, Wright Foods has the experience to produce customized products to fit customers specifications, from concept to plate.





Xanofi, Inc.

Xanofi, Inc. is developing Shear Multiplying (TM) –  a novel method for producing nanofibers with a wet-spinning technique.  Shear Multiplying produces high yields at low cost and features the ability to integrate additives to create functional, unique fibers.






Yamco LLC is a food processing company formed by seven North Carolina agribusiness growers who collectively produce and manage a substantial portion of North Carolina’s sweet potato crop.






ZettaCore is focused on molecular memory applications. Our technology will lead to significant advances in memory capability, playing a key role in new generations of electronic devices, both large and small.





Zenomics is a company dedicated to developing innovative drug delivery systems that enhance health and improve quality of life. The company focuses on the development of the transformative glucose-responsive insulin delivery devices for intelligently controlling release of insulin and regulating blood sugar levels for people with diabetes.