{"id":454,"date":"2021-03-04T15:43:52","date_gmt":"2021-03-04T15:43:52","guid":{"rendered":"https:\/\/dev.research.ncsu.edu\/metric-alt\/?page_id=454"},"modified":"2021-03-04T15:43:52","modified_gmt":"2021-03-04T15:43:52","slug":"macromolecular","status":"publish","type":"page","link":"https:\/\/research.ncsu.edu\/metric\/x-ray-crystallography\/macromolecular\/","title":{"rendered":"Macromolecular X-ray Crystallography"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/dev.research.ncsu.edu\/metric-alt\/wp-content\/uploads\/2022\/03\/metric-2624-1024x683.jpg\" alt=\"\" class=\"wp-image-787\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":273,"featured_media":0,"parent":121,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/default-header","ncst_dynamicHeaderData":"{\"pageIntro\":\"X-ray crystallography is an analytical method of determining the three-dimensional structure of a molecule resulting in a set of coordinates describing the location of non-hydrogen atoms in the molecule.\u00a0 Macromolecular X-ray crystallography focuses on very large biological molecules such as proteins, DNA and RNA.\u00a0 The three-dimensional structures are used to understand the relationship between the structure of a biological molecule and its function.\u00a0It is also used to understand the interactions between interacting biological molecules, and between biological molecules and small molecules such as substrates, inhibitors, and pharmaceuticals.\u00a0Macromolecular X-ray crystallography also is used to study the structural effects of mutations in proteins, the effect those mutations have on the structure-function relationship, protein stability, and in protein engineering.\"}","ncst_content_audit_freq":"","ncst_content_audit_date":"","ncst_content_audit_display":false,"ncst_backToTopFlag":"","footnotes":""},"tags":[],"class_list":["post-454","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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