{"id":1320,"date":"2022-04-11T14:29:22","date_gmt":"2022-04-11T14:29:22","guid":{"rendered":"https:\/\/research.ncsu.edu\/metric\/?p=1320"},"modified":"2022-04-11T14:35:04","modified_gmt":"2022-04-11T14:35:04","slug":"the-value-of-15n-nmr-spectroscopy","status":"publish","type":"post","link":"https:\/\/research.ncsu.edu\/metric\/2022\/04\/11\/the-value-of-15n-nmr-spectroscopy\/","title":{"rendered":"The value of 15N NMR spectroscopy"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">NMR detection of <sup>13<\/sup>C and <sup>1<\/sup>H are well known and commonly used by scientists, but <sup>15<\/sup>N is often forgotten, due to its low natural abundance and sensitivity. However, with the state-of-art instrumentation and innovative technology in METRIC, <sup>15<\/sup>N NMR can be a super useful tool to provide extremely valuable information to characterize nitrogen-containing molecules and bio-molecules. Through the investigation of multiple parameters including <sup>15<\/sup>N chemical shift, <sup>1<\/sup>H-<sup>15<\/sup>N coupling constants, and <sup>15<\/sup>N relaxation studies, these valuable data can reveal the stereochemistry, structure, and dynamics in various cases such as hydrogen bond conformation, tautomerism, protonation, metal complexation, and others.<br><br>Need more details? Or don\u2019t know whether <sup>15<\/sup>N may help your research? Please <a href=\"https:\/\/go.ncsu.edu\/metricmrconsult\">contact<\/a> the METRIC NMR Team through MENDIX. We would be more than happy to discuss how <sup>15<\/sup>N NMR can help advance your projects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NMR detection of 13C and 1H are well known and commonly used by scientists, but 15N is often forgotten, due to its low natural abundance and sensitivity. However, with the&hellip;<\/p>\n","protected":false},"author":244,"featured_media":1321,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/default-post-header","ncst_dynamicHeaderData":"{\"showAuthor\":true,\"showDate\":true,\"showFeaturedVideo\":false,\"caption\":\"\",\"subtitle\":\"Do you have a nitrogen-containing molecule that has been difficult to identify or characterize? If so, consider trying <sup>15<\/sup>N NMR spectroscopy in NCSU METRIC NMR Laboratory. \",\"displayCategoryID\":4}","ncst_content_audit_freq":"","ncst_content_audit_date":"","ncst_content_audit_display":false,"ncst_backToTopFlag":"","footnotes":""},"categories":[4],"tags":[],"_ncst_magazine_issue":[],"class_list":["post-1320","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nmr"],"displayCategory":{"term_id":4,"name":"NMR","slug":"nmr","term_group":0,"term_taxonomy_id":4,"taxonomy":"category","description":"","parent":0,"count":4,"filter":"raw"},"acf":{"ncst_posts_meta_modified_date":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The value of 15N NMR spectroscopy - METRIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.ncsu.edu\/metric\/2022\/04\/11\/the-value-of-15n-nmr-spectroscopy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The value of 15N NMR spectroscopy - METRIC\" \/>\n<meta property=\"og:description\" content=\"NMR detection of 13C and 1H are well known and commonly used by scientists, but 15N is often forgotten, due to its low natural abundance and sensitivity. 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