{"id":15942,"date":"2023-04-13T11:29:47","date_gmt":"2023-04-13T15:29:47","guid":{"rendered":"https:\/\/research.ncsu.edu\/rdo\/?page_id=15942"},"modified":"2023-09-29T13:05:53","modified_gmt":"2023-09-29T17:05:53","slug":"arpa-h-opportunities","status":"publish","type":"page","link":"https:\/\/research.ncsu.edu\/rdo\/pdu\/pdu-resources\/arpa-h-opportunities\/","title":{"rendered":"ARPA-H Opportunities"},"content":{"rendered":"\n\n\n\n\n<ul class=\"wp-block-list\">\n<li>Program Manager-driven funding opportunities, typically with a white paper\/invitation to submit phase.&nbsp;<\/li>\n\n\n\n<li>Nimble project management, with gated milestones (i.e. opportunities to fail fast).&nbsp;<\/li>\n\n\n\n<li>Focus on application &#8211; could the research outcome be impacting the world in 5-10 years?<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Finding ARPA-H Funding<\/h2>\n\n\n\n<p>Most ARPA-H programs will be announced through <a href=\"https:\/\/sam.gov\/\">SAM.gov<\/a>. Select Search &gt; Select Domain: Contract Opportunities &gt; Filter by Keyword \u201cARPA-H\u201d (Exact Phrase).&nbsp;<\/p>\n\n\n\n<p>ARPA-H has also announced their new programs on their <a href=\"https:\/\/arpa-h.gov\/news\/\">News Page<\/a>.<\/p>\n\n\n\n<p>Note: Although part of NIH, because ARPA-H will not be using the standard NIH grant mechanisms, calls for funding will likely not be announced in the NIH Guide for Grants and Contracts or Grants.gov.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">NC State Resources for ARPA-H<\/h2>\n\n\n\n<p>Proposal Development Unit Webinar: <a href=\"https:\/\/drive.google.com\/file\/d\/1xqzqyEt97QJP30PfPNy1_uC84JcDdYo9\/view?usp=share_link\">NIH@NC State: ARPA-H\u2019s First BAA, March 30, 2023<\/a>, <a href=\"https:\/\/drive.google.com\/file\/d\/1Df3wDJbUvtxpPg2hK9B27PrazwnJRb3_\/view?usp=share_link\">Slides<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">FAQs for Applying to ARPA-H&nbsp;<\/h2>\n\n\n<div class=\"wp-block-ncst-accordion ncst-accordion\"><div class=\"accordion\" id=\"ncst-accordion-0\"><div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-0\" id=\"ncst-accordion-item-heading-0\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-0\" aria-controls=\"ncst-accordion-item-0-0\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">Do I need to do anything special for the Abstract\/White Papers\/Pre-Proposals?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-0\" aria-labelledby=\"ncst-accordion-item-heading-0\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>Because of the unique award terms and conditions that may come with ARPA-H awards, NC State ORI is asking that White Papers \/ Preproposals are captured in PINS as Pre-proposals.&nbsp;<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-1\" id=\"ncst-accordion-item-heading-1\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-1\" aria-controls=\"ncst-accordion-item-0-1\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">How do I handle a PINS\/RADAR record for ARPA-H Proposals?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-1\" aria-labelledby=\"ncst-accordion-item-heading-1\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>Select \u201cAdvanced Research Projects Agency for Health (ARPA-H)\u201d as your Primary Sponsor (not NIH). If you are submitting a Full Proposal, subsequent to an invited Abstract, include the linked RADAR\/PINS #s from your Abstract submission.&nbsp;<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-2\" id=\"ncst-accordion-item-heading-2\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-2\" aria-controls=\"ncst-accordion-item-0-2\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">How do I submit an ARPA-H Proposal?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-2\" aria-labelledby=\"ncst-accordion-item-heading-2\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>Refer to the instructions in the Broad Agency Announcement (BAA) or Notification of Funding Opportunity (NOFO) for specific information. If your proposal requires submission through a system other than eRA Commons\/grants.gov, such as the NIH eCPS, reach out to your College Research Office well in advance to set up new log-in credentials. Establishing log-in credentials in new agency portals can take several weeks.&nbsp;Also, per NC State SPARCS Standard Operating Procedures, all applications (which includes ARPA-H abstracts) should be submitted by someone with delegated authority to submit applications. Therefore, even if the system would physically allow PIs to submit applications, it is important to have an authorized CRO AOR actually submit the proposals.&nbsp;&nbsp;<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-3\" id=\"ncst-accordion-item-heading-3\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-3\" aria-controls=\"ncst-accordion-item-0-3\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">The ARPA-H BAA asks me to indicate if I prefer a Cooperative Agreement, Other Transaction, or Contract; are there any recommendations for which direction I should go?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-3\" aria-labelledby=\"ncst-accordion-item-heading-3\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>In general, each option will trigger different compliance requirements, but in all three options, the expectation is that the Federal Program Manager will be more heavily engaged in the research than a team might expect from a traditional grant. In all cases, the Government Contracting Officers\/Agreements Officers\/Other Transaction Agreements Officers shall have sole discretion to select award instrument type, regardless of the instrument type proposed, and to negotiate all instrument terms and conditions with NC State.<strong>&nbsp;&nbsp;<\/strong><\/p>\n\n\n\n<p>It is highly recommended that investigators meet with their College Research Office and SPARCS Negotiations team, prior to submitting a request for one mechanism or another.&nbsp; <strong>In most cases, NC State will encourage teams to use a cooperative&nbsp;agreement<\/strong>. Some things to consider:<\/p>\n\n\n\n<p>Cooperative Agreements are federal assistance mechanisms. Typically, they will invoke standard terms and conditions (such as the NIH Grants Policy Statement or 2 CFR 200), and have a research product intended for the public good. Because cooperative agreements are the most similar to traditional grant mechanisms, this may be the least complicated option if privacy\/transparency or IP ownership are not significant concerns for the given project.&nbsp;<\/p>\n\n\n\n<p>An Other Transaction (OT) is like a Cooperative Agreement, but invokes non-standard terms and conditions. While this may provide more flexibility to the research team over the course of the project, there will be a considerable negotiation period up front.<\/p>\n\n\n\n<p>Contracts are federal acquisition mechanisms. Typically they are used when the government is interested in purchasing\/owning some technology. They will invoke the Federal Acquisition Regulations, rather than the Uniform Grants Guidance, and may be especially relevant when areas such as IP management are in consideration.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-undefined-4\" id=\"ncst-accordion-item-heading-4\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-undefined-4\" aria-controls=\"ncst-accordion-item-undefined-4\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">Because ARPA-H is interested in applying innovations, I think my proposal would be strengthened with a collaboration with one or more health-care systems. Are there any resources at NC State that can connect me to medical collaborators?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-undefined-4\" aria-labelledby=\"ncst-accordion-item-heading-4\"><div class=\"accordion-item__content\">\n<p>The Research Development Office has several standing arrangements with organizations such as UNC School of Medicine, Lineberger Cancer Center, and the Duke Clinical and Translational Science Institute. If you are interested in assistance in reaching out to local medical organizations, you can contact Jonathon Horowitz or Pradip Pramanik in <a href=\"https:\/\/research.ncsu.edu\/rdo\/contact\/\">RDO<\/a>.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-undefined-5\" id=\"ncst-accordion-item-heading-5\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-undefined-5\" aria-controls=\"ncst-accordion-item-undefined-5\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">ARPA-H\u2019s First BAA includes the language \u201cEntities with more than three ongoing concurrent awards with ARPA-H will not be eligible for award.\u201d Does that mean this is a limited submission?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-undefined-5\" aria-labelledby=\"ncst-accordion-item-heading-5\"><div class=\"accordion-item__content\">\n<p>At this point, the NC State Limited Submissions Office is not treating this as a limited submission project, because ARPA-H will accept unlimited NC State submissions until three have been awarded.&nbsp;<\/p>\n\n\n\n<p>However, we recognize that teams do not want to spend time working on a proposal that has no chance of being funded because the cap is met. Therefore, we encourage all teams to: 1) create a PINS record early in the process, indicating ARPA-H as the primary sponsor so that ORI units are aware of your interest. 2) Reach out to the Proposal Development Unit for a consultation during the initial Abstract phase, to get an assessment of competitiveness. 3) Reach out to your College Research Offices to help conduct a RADAR search of currently active NC State ARPA-H awards.&nbsp;4) Consider a Cooperative Agreement mechanism, rather than a Contract mechanism, as the 3-award cap specifically applies to FAR-based contracts.&nbsp;&nbsp;<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-6\" id=\"ncst-accordion-item-heading-6\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-6\" aria-controls=\"ncst-accordion-item-0-6\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">I have a great idea for a biomedical innovation &#8211; should I send it to NIH or ARPA-H?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-6\" aria-labelledby=\"ncst-accordion-item-heading-6\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>While both agencies fund biomedical research, NIH is focused on building the foundational knowledge base of human health and biomedical science, while ARPA-H is focused on high-impact innovations to potentially shift the paradigm of human health. Some questions to ask yourself: 1) Would this project require a long-term investment, such as a 10-year longitudinal study? (If so, consider NIH.) 2) Would go\/no-go milestones make sense as a way to assess this project? (If no, this would not be appropriate for ARPA-H.) 3) Am I worried that other researchers in my field may \u201cscoop\u201d this project? (If so, this may indicate NIH-style incremental research). 4) Is this project very specific to a single disease or condition? (If so, consider NIH.)<\/p>\n\n\n\n<p>If you are not sure, both NIH and ARPA-H would strongly recommend you reach out to Program Officers\/Program Managers and have a conversation about your goals and research interests. Additionally, NC State researchers can <a href=\"https:\/\/intranet.research.ncsu.edu\/pdu\/request-pdu-services\/\">request a consultation<\/a> with the PDU if they would like help talking through their options and planning to contact Program Officers.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-ncst-accordion-item ncst-accordion-item panel\"><a class=\"accordion-item__header collapsed\" href=\"#ncst-accordion-item-0-7\" id=\"ncst-accordion-item-heading-7\" data-toggle=\"collapse\" data-target=\"#ncst-accordion-item-0-7\" aria-controls=\"ncst-accordion-item-0-7\" rel=\"noopener noreferrer\"><span class=\"accordion-item__expansion-indicator\"><span class=\"ncst-plus-minus-toggle\"><\/span><\/span><h2 class=\"accordion-item__label h5\">What Study Section will my ARPA-H application be sent to?<\/h2><\/a><div class=\"collapse panel-collapse accordion-item__content-container \" id=\"ncst-accordion-item-0-7\" aria-labelledby=\"ncst-accordion-item-heading-7\" data-parent=\"#ncst-accordion-0\"><div class=\"accordion-item__content\">\n<p>ARPA-H will not be utilizing the standard NIH Center for Scientific Review peer review groups. Rather, ARPA-H Program Managers will be responsible for reviewing each application, soliciting subject matter expertise as necessary. Teams should not expect to receive a standard Summary Statement back from review; rather they will either be declined or invited to submit\/negotiate an award. Teams should take this review model into consideration when writing their proposals.<\/p>\n<\/div><\/div><\/div>\n\n<\/div><\/div>\n\n\n\n\n<p>If you have any additional questions that you would like to be considered for the FAQ page, please reach out to Molly Puente, Proposal Development Unit (mepuente@ncsu.edu).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Finding ARPA-H Funding Most ARPA-H programs will be announced through SAM.gov. Select Search &gt; Select Domain: Contract Opportunities &gt; Filter by Keyword \u201cARPA-H\u201d (Exact Phrase).&nbsp; ARPA-H has also announced their&hellip;<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":304,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/default-header","ncst_dynamicHeaderData":"{\"pageIntro\":\"As one of the newest federal funding agencies, <a href=\\\"https:\/\/arpa-h.gov\/\\\">ARPA-H<\/a> provides researchers with funding opportunities designed to accelerate radical, game-changing ideas to improve the U.S. healthcare system. While part of the NIH, ARPA-H follows the government ARPA model, with the following key features.\"}","ncst_content_audit_freq":"","ncst_content_audit_date":"","ncst_content_audit_display":false,"ncst_backToTopFlag":"","footnotes":""},"tags":[],"class_list":["post-15942","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ARPA-H Opportunities - Research Development Office<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.ncsu.edu\/rdo\/pdu\/pdu-resources\/arpa-h-opportunities\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ARPA-H Opportunities - Research Development Office\" \/>\n<meta property=\"og:description\" content=\"Finding ARPA-H Funding Most ARPA-H programs will be announced through SAM.gov. 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