Several major research institutions have been cited by the federal Office for Human Research Protection (OHRP) for non-compliance with federal regulations regarding the use of human subjects in research. Subsequently, the privileges to conduct research using human subjects and to expend federal funds were temporarily suspended for these institutions. To avoid non-compliance, OHRP strongly recommends that educational programs are completed by anyone involved in human subject research. Other agencies, such as the National Institutes of Health (NIH) requires proof of human subject research education for all key personnel on any NIH funded projects. National Science Foundation (NSF) requirements mandate NC State University undergraduate students, graduate students, and postdoctoral researchers to complete training in the Responsible Conduct of Research (RCR).

The NC State Institutional Review Board (IRB) supports recommendations and requirements of federal agencies and encourages everyone involved in human subject research to complete educational programs. Below are links to well-established programs which should be utilized to avoid research problems and ultimately make IRB interactions more efficient.

If you have any questions or comments, please feel free to contact the IRB office at 919-515-7515.

 Readings for Discussion: Research Ethics and Compliance

Many issues related to research ethics and compliance are new, ever growing, complex, and nuanced. Just as each study is unique, the ethical considerations and issues of compliance are as well. The NC State IRB office has selected some readings for your research team to read through and discuss. Reading these articles and discussing them with your team(s) and/or students will help illuminate some nuances regarding ethics and compliance related to research activities. We suggest reading through them and talking about issues of informed consent, participant selection, research design, analysis of risks, and understanding of national and local contexts related to the issues brought up.

With the Best Intentions: Lead Research and the Challenge to Public Health

Protecting Third Parties in Human Subjects Research