Allen Distinguished Microscopy Seminar

Live and in color: Improved tools for multi-parameter imaging

Karin Schumacher, Ph.D, Professor,
Plant Developmental Biology, Centre for Organismal Studies
Heidelberg University, Heidelberg, Germany

Sponsored By:
ORIED, CALS, COS, CVM, COE & Eastman Chemical University Engagement Fund

Abstract: The concentration of two ions, Ca2+ and H+, affects almost all biological processes, and dynamic changes in [Ca2+] and pH are integral components of many signaling pathways. My lab studies the transport machinery that controls cellular pH and Ca2+ -homeostasis and we use genetically-encoded sensors to visualize their spatio-temporal dynamics. In my presentation, I will cover our recent work on pH-regulation in the plant endomembrane system as well as our attempts to establish transgenic lines that allow monitoring of multiple parameters including pH, Ca2+, ROS and ATP.