Area(s) of Expertise

Leonard became a Research Specialist at UNC-Chapel Hill in 2006 and worked in the Biomarker Mass Spectrometry facility until arriving at NC State in 2020. Leonard has experience developing mass spectrometry methods for DNA and RNA oligos, DNA damage products, single nucleotides, intact proteins and peptides, natural molecules and metabolites, drugs and metabolites, and environmental contaminants such as PAHs and PFAS.

Publications

• Hydrodistillation-Based Essential Oil Extraction and Soda Pulping of Spent Hemp Biomass for Sustainable Fiber Production , Molecules (2026)
• Adrenodoxin alters human cytochrome P450 27A1 structure and reaction efficiency beyond supplying electrons , Archives of Biochemistry and Biophysics (2025)
• Illuminating the mechanistic impacts of an Fe-quaterpyridine functionalized crystalline poly(triazine imide) semiconductor for photocatalytic CO ₂ reduction , Inorganic Chemistry Frontiers (2025)
• Injection of vocal fold lamina propria-derived hydrogels modulates fibrosis in injured vocal folds , Biomaterials Advances (2025)
• Smartphone-Based Colorimetric VOC Sensor for Early Detection of Phytophthora Ramorum in Rhododendrons , ACS Sensors (2025)
• Use of Synthetic Standard Peptides in Standardized Digests to Evaluate Both Sample and Instrument Suitability in Proteomics , Journal of Proteome Research (2025)
• A Multi-enzyme Protocol Improves Total Proteome Coverage in Extracellular Matrix , Methods in Molecular Biology (2024)
• Human Cell‐Derived Matrix Composite Hydrogels with Diverse Composition for Use in Vasculature‐on‐chip Models , Advanced Healthcare Materials (2024)
• Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis , Frontiers in Immunology (2024)
• The biochemical effects of carotenoids in orange carrots on the colonic proteome in a mouse model of diet-induced obesity , Frontiers in Nutrition (2024)

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Groups

• Mass Spectrometry