![](https://research.ncsu.edu/administration/files/2023/07/20230712_IACUC-LifeCycle_Step3.png)
Step 3: Application Review Process
New protocol submissions and amendment requests for approved protocols are submitted to the IACUC office by the Principal Investigator. Significant Protocol amendment requests are processed and reviewed the same as new protocols.
Types of Review
- Pre-review, Designated Member review and full committee reviews for new protocols submissions, 3-year rewrites and amendments
- Administrative Review Procedures
How to Address Comments on Your Protocol
These resources cover how to address comments made by IACUC reviewers on a protocol that has already been approved
Estimated Review Timeframe for Protocols and Amendments
Full committee meetings are held on the third Thursday of each month. New protocols should be submitted at least 2 weeks in advance to allow pre-review of the submission.
- Full Committee Review Approval (New Category E protocols or amendments): 6-7 weeks
- Designate Member Review Approval (Amendments with significant changes or Category C/D protocols): 3-5 weeks
- Administrative Review (Amendments with minor changes): same day to 1 week
These timeframes are for planning purposes only. Some protocols may be completed sooner or take longer, depending on the details.